Xin Li

Selective bHLH relay factors and modular enhancers decode Notch signaling during neuronal diversification in the Drosophila medulla

The paper identifies how Notch signaling generates diverse neuronal fates through modular enhancers and distinct bHLH factors that decode Notch status via different E-box motifs.

A Notch-dependent transcriptional mechanism controls expression of temporal patterning factors in Drosophila medulla

The paper shows that Notch signaling regulates the transcription of temporal patterning factors in Drosophila neuroblasts, linking cell cycle progression to temporal transitions.

A comprehensive temporal patterning gene network in Drosophila medulla neuroblasts revealed by single-cell RNA sequencing

The paper uses single-cell RNA sequencing to study temporal patterning in Drosophila medulla neuroblasts, identifying novel transcription factors and revealing a comprehensive gene network governing temporal progression and cell cycle exit.

Netrins and receptors control Drosophila optic lobe organization and transmedullary neuron axon targeting

The paper shows that Notch-dependent fate choice in Drosophila medulla neurons regulates Netrin expression, which controls axon guidance and neuropil organization in the optic lobe.