Xiangdong Chen

RodZ acts through MreBCD to activate the elongasome in Escherichia coli

This study identifies RodZ's role in activating the elongasome in E. coli by interacting with MreB and MreCD, switching MreBCD to an active state to stimulate PG synthesis.

A self-organized geometry sensing oscillator spatially regulates cell division in archaea

This paper identifies a geometry sensing oscillator in archaea that spatially regulates cell division, showing convergent evolution with bacterial systems.

Systematic identification of cell division proteins in haloarchaea and the discovery of a membrane anchor for the Z ring

This study identifies ten cell division proteins in Haloferax volcanii using CLIP-MS, with CdpC functioning as a membrane anchor for FtsZ1 and containing zinc fingers critical for its role.

ZapA employs a two-pronged mechanism to facilitate Z ring formation in Escherichia coli

This study identifies how ZapA interacts with FtsZ to facilitate Z ring formation in E. coli by using a dual binding mechanism.

ZapC crosslinks FtsZ filaments through a dual-binding mechanism modulated by the intrinsically disordered linker of FtsZ

This paper identifies a dual-binding mechanism by which ZapC crosslinks FtsZ filaments, with the FtsZ C-terminal linker modulating interactions with ZapC and other proteins.

4-hydroxyphenylpyruvate dioxygenase thermolability is responsible for temperature-dependent melanogenesis in Aeromonas salmonicida subsP salmonicida

This paper identifies the thermolability of 4-hydroxyphenylpyruvate dioxygenase (HppD) as the cause of temperature-dependent melanogenesis in Aeromonas salmonicida subsp. salmonicida.