Author

Derek Holman

Stanford MedicineORCID 0000-0002-3482-832XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

John Mark B. GubataniD· 2 shared Stephan RogallaiD· 2 shared Allen NguyeniD· 1 shared Amelia Au‐Yeung· 1 shared Chikara Takahashi· 1 shared Courtney SchiffmaniD· 1 shared Garry P. NolaniD· 1 shared Gustavo Vazques· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

John Mark B. GubatanORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 23, 2026

Single-cell profiling reveals stromal niche and α5β1 regulation of neutrophil phenotypes in ulcerative colitis

Yuxi Zhou, Jorge Canas, Jiayu Ye…·John Mark B. Gubatan

This study uses single-cell RNA sequencing and spatial profiling to show fibroblasts influence neutrophil inflammation in UC, with 5β1 targeting reducing inflammatory responses.

DOI 10.64898/2026.09.21.753318

humanmouse

ImmunologybioRxivPreprintJul 2, 2024

Molecular characterization of response to etrolizumab and anti-TNF reveals treatment resistance in ulcerative colitis is associated with the abundance of residual neutrophil subsets and inflammatory fibroblast populations

Shadi Toghi Eshghi, John Mark B. Gubatan, Parisa Mazrooei…·Jacqueline McBride

The paper identifies treatment resistance in ulcerative colitis linked to residual neutrophil subsets and inflammatory fibroblasts using single-cell analysis of biopsy data.

3 citations

humanscRNA-seq

Developmental BiologyPlacentaPeer-reviewedAug 23, 2022

Infection with Listeria monocytogenes alters the placental transcriptome and eicosanome

Kayla N. Conner, Derek Holman, Todd A. Lydic, Jonathan W. Hardy

This study shows that Listeria monocytogenes infection alters placental gene expression and eicosanoid levels, potentially explaining preterm labor and suggesting biomarkers for intervention.

6 citations

mousebulk RNA-seq