Jiayu Ye

This study creates a single-cell immune repertoire atlas in IBD patients, revealing coordinated immune states and identifying potential therapeutic targets.

This study uses single-cell RNA sequencing and spatial profiling to show fibroblasts influence neutrophil inflammation in UC, with 5β1 targeting reducing inflammatory responses.

This study identifies Gpr37 as a gene expressed in enteric glia cells of the myenteric plexus and shows its role in LPS-induced reactive gliosis and GI dysmotility.

This paper introduces a bio-engineered probiotic with a persistence feature that improves efficacy in colitis models, showing reduced inflammation and enhanced mucosal healing.