Author

Ícaro Maia Santos de Castro

Universidade de São PauloORCID 0000-0002-3484-8718Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Helder Imoto NakayaiD· 2 shared Izabela MamedeiD· 2 shared Andre Ferreira CunhaiD· 1 shared Eurico de Arruda Neto· 1 shared Francisco Vásquez· 1 shared Glória Regina FrancoiD· 1 shared João Carlos SetúbaliD· 1 shared Lívia Cavalcanti de Morais Gama· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Helder Imoto NakayaORCID

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2 papers

Recent·Most cited

Multi-scale Transcriptional Characterization of HPV16 and HPV18 in Cervical Cancer: Host Pathway Alterations and Links With Viral Gene Expression Programs

Marcela Akemi Ishihara, Maiara Mascarenhas Moro Valeriano, Noilson Oliveira, Izabela Mamede, Lívia Cavalcanti de Morais Gama, Andre Ferreira Cunha, Ícaro Maia Santos de Castro, Francisco Vásquez, Milton Yutaka Nishiyama, João Carlos Setúbal, Eurico de Arruda Neto, Roger J. Chammas, Helder Imoto Nakaya

This study compares HPV16 and HPV18 cervical cancers using gene expression data to identify genotype-specific host pathway alterations and viral gene expression programs.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology

SARS-CoV-2 selectively induces the expression of unproductive splicing isoforms of interferon, class I MHC and splicing machinery genes

Thomaz Lüscher Dias, Izabela Mamede, Nayara Evelin de Toledo, Lúcio Rezende Queiroz, Ícaro Maia Santos de Castro, Rafael B. Polidoro, Luiz‐Eduardo Del‐Bem, Helder Imoto Nakaya, Glória Regina Franco

This study identifies that SARS-CoV-2 increases unproductive splicing isoforms of immune-related genes, potentially subverting antiviral responses.

International Journal of Molecular Sciences · May 23, 2024Peer-reviewedBioinformatics