Distinct chromatin scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2
Jonathan Lerner, Andrew Katznelson, Jingchao Zhang, Kenneth S. Zaret
The paper shows that pioneer factors FOXA1 and SOX2 use distinct chromatin scanning dynamics to target compacted chromatin, while non-pioneer HNF4A targets open chromatin regions.
bioRxiv · Dec 22, 2022 · PreprintMolecular Biology