Non-viral gene editing in utero with lipid nanoparticles complexed to mRNA
Kewa Gao, Jie Li, Hengyue Song, Hesong Han, Yongheng Wang, Boyan Yin, Diana Lee Farmer, Niren Murthy, Aijun Wang
This study demonstrates that lipid nanoparticles can deliver mRNA for gene editing enzymes in utero, effectively editing multiple organs with low toxicity.
bioRxiv · Oct 14, 2022 · PreprintGenetics