Microglial-Mediated Prevention of Axonal Degeneration in the Injured Spinal Cord: Insights from an In Vivo Imaging Study
Wanjie Wu, Yingzhu He, Yujun Chen, Yiming Fu, Sicong He, Kai Liu, Jianan Y. Qu
This study shows microglia prevent axonal degeneration after spinal cord injury by wrapping injured axons, a process dependent on P2Y12 receptors and sodium channels.
bioRxiv · Apr 13, 2024 · PreprintNeuroscience