Pharmacology & ToxicologyJournal of the American Heart AssociationPeer-reviewed
Coronary Microvascular Dysfunction is Associated with Augmented Lysosomal Signaling in Hypercholesterolemic Mice
Yunting Wang, Alexandra K. Moura, Rui Min Zuo…·Xiang Li
This study shows that hypercholesterolemia causes coronary microvascular dysfunction in mice through enhanced lysosomal signaling in endothelial cells, which can be mitigated by ezetimibe.