Vertical transmission of maternal DNA through extracellular vesicles associates with altered embryo bioenergetics during the periconception period
David Bolumar, Javier Moncayo, Javier González-Fernández, Ana Ochando, Inmaculada Moreno, Ana Monteagudo, Carlos Marin, Antonio Diez, Paula Fabra, Miguel Ángel Checa, Juan José Espinós, David K. Gardner, Carlos Simón, Felipe Vilella
The paper investigates DNA transfer via extracellular vesicles from maternal endometrium to embryos, showing altered embryo bioenergetics.
bioRxiv · Apr 21, 2023 · PreprintDevelopmental Biology