Felipe Vilella

Modeling human embryo adhesion using a microfluidic platform

This paper presents a microfluidic platform to model human embryo adhesion and endometrial interactions, showing embryo-epithelial contacts and hormone-induced receptivity.

Full-thickness spatial transcriptomics of the human uterus reveals basalis niche architecture and regeneration gradients during menstrual breakdown

This study uses spatial transcriptomics to map gene expression gradients in the human endometrium, revealing coordinated regeneration and niche architecture during menstrual breakdown.

An integrated multimodal pan-organ atlas of the female reproductive system across the lifespan contextualises gynaecological pathologies

This paper creates an integrated multimodal atlas of the female reproductive system across the lifespan, identifying cell types and linking them to gynaecological pathologies.

Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis Patients

The paper uses single-cell transcriptomics to analyze endometrial cells from endometriosis patients, revealing altered cellular features and immune communication networks across the menstrual cycle.

Vertical transmission of maternal DNA through extracellular vesicles associates with altered embryo bioenergetics during the periconception period

The paper investigates DNA transfer via extracellular vesicles from maternal endometrium to embryos, showing altered embryo bioenergetics.

Single cell RNAseq provides a molecular and cellular cartography of changes to the human endometrium through the menstrual cycle

The paper uses single-cell RNA sequencing to map gene expression changes in the human endometrium across the menstrual cycle, identifying distinct cell types and their transcriptional signatures.

Endometrial receptivity revisited: endometrial transcriptome adjusted for tissue cellular heterogeneity

The paper investigates how cellular composition affects endometrial gene expression profiles and shows that adjusting for cell proportions changes differential expression results.