Integrated Dual-Channel Retrograde Signaling Directs Stress Responses by Degrading the HAT1/TPL/IMPalpha-9 Suppressor Complex and Activating CAMTA3
Liping Zeng, Jingzhe Guo, Malathy Palayam, Carlos Rodríguez, Maria Fernanda Gomez Mendez, Yaqi Wang, Wilhelmina van de Ven, José L. Pruneda-Paz, Nitzan Shabek, Katayoon Dehesh
This study identifies MEcPP as a stress-induced metabolite that disrupts the HAT1/TPL/IMP-9 suppressor complex, releasing CAMTA3 and enabling Ca2+ influx to activate stress responses.
The Plant Journal · Sep 1, 2025Peer-reviewedPlant Biology