Author

Ren Xu

University of KentuckyORCID 0000-0002-3591-9522Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ren Xu1 paper · Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University;

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Akshat GuptaiD· 1 shared Baorui Kang· 1 shared Dalton Hironaka· 1 shared Dongsung Kim· 1 shared Gaofeng Xiong· 1 shared Haichang LiiD· 1 shared Jinpeng LiuiD· 1 shared Ke CheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Akshat GuptaORCID

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2 papers

Recent·Most cited

P4HA1 sustains endocrine resistance in luminal breast cancer via regulation of cellular stress

Dalton Hironaka, Baorui Kang, Dongsung Kim, Haichang Li, Rachel Schiff, Ren Xu, Gaofeng Xiong

This study identifies P4HA1 as a driver of endocrine resistance in luminal breast cancer by promoting cellular stress, showing that targeting P4HA1 can restore hormone sensitivity.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology

Single-Cell Analysis of Gene Regulatory Networks in the Mammary Glands of P4HA1-knockout mice

Akshat Gupta, Lilin Huang, Jinpeng Liu, Ke Chen, Ren Xu, Wei Wu

This study uses single-cell RNA sequencing and the SCENIC pipeline to analyze gene regulatory networks in P4HA1-knockout mice, identifying unique regulatory patterns in control mice linked to stem cell and inflammatory pathways.

PLoS Genetics · Jul 22, 2025Peer-reviewedBioinformatics