Harald Surowy

Breast cancer risks associated with missense variants in breast cancer susceptibility genes

The paper assesses breast cancer risks linked to rare missense variants in five susceptibility genes using logistic and mixture models, finding varying risk contributions across genes.

A human multisystem disorder with autoinflammation, leukoencephalopathy and hepatopathy is caused by mutations in C2orf69

The paper identifies mutations in the C2orf69 gene as the cause of a human multisystem disorder characterized by autoinflammation, leukoencephalopathy, and hepatopathy.

Dissection of demethylation and toxicity induced gene expression changes after decitabine treatment.

This study examines how decitabine affects DNA methylation and gene expression in cancer cells, revealing dose-dependent demethylation and toxicity effects on gene regulation.