The action mechanism of actinoporins revealed through the structure of pore-forming intermediates
Rocío Arranz, César A. Santiago, Simonas Masiulis, Esperanza Rivera‐de‐Torre, Juan Palacios‐Ortega, Diego Carlero, Diego Heras‐Márquez, José G. Gavilanes, Ernesto Arias‐Palomo, Álvaro Martínez‐del‐Pozo, Sara García‐Linares, Jaime Martín‐Benito
The paper determines the structures of two actinoporins in a membrane environment using cryogenic electron microscopy, revealing their pore-forming mechanism through intermediate states.
Science Advances · Sep 24, 2025Peer-reviewedBiochemistry