Magdalena A. Budzinska

mRNArchitect is a software toolkit for designing and optimising mRNA sequences to improve translation, stability, and immunogenicity, validated across multiple cell types and tissues.

This study uses deep learning to segment tumor microenvironments in lung cancer images, predicting patient survival and gene mutations with moderate to high accuracy.

SLIDE-VIP identifies synthetic lethal gene pairs in DNA damage repair, chromatin remodeling, and cell cycle using multi-omics data and eight statistical tests, reducing candidate pairs by 250-fold.