Molecular BiologybioRxivPreprint
In Silico-Driven Engineering of Halomonas elongata L-Asparaginase: Towards Enhanced Proteolytic Resistance in Lymphoblastic Leukemia
Maryam Samadaei Ghadikolaei, Sedigheh Asad, Vahideh Hassan‐Zadeh
This paper enhances the proteolytic resistance of Halomonas elongata L-asparaginase through site-directed mutagenesis, resulting in a mutant with increased activity and serum stability.
DOI 10.1101/2024.06.07.597648