Quantifying B-cell Clonal Diversity In Repertoire Data
Aurélien Pélissier, Siyuan Luo, Maria Stratigopoulou, Jeroen E. J. Guikema, María Rodríguez Martínez
This study compares clone identification methods for B-cell repertoires and finds Shannon entropy to be the most robust diversity index, with alignment-free methods preferred for shorter reads.
Frontiers in Immunology · Apr 17, 2023Peer-reviewedBioinformatics