Glycolysis and hexosamine biosynthesis pathways are key for inflammatory protein maturation and leukocyte adhesion to human aortic valve cells
Tania Sánchez‐Bayuela, Mirian Peral-Rodrigo, Javier López, Cristina Gómez, Enrique Pérez-Riesgo, Natalia López‐Andrés, Nieves Fernández, J. Alberto San Román, Mariano Sánchez Crespo, Carmen García‐Rodríguez
This study shows glycolysis and the hexosamine biosynthesis pathway are essential for inflammatory protein maturation and leukocyte adhesion in aortic valve cells during calcific aortic valve disease.
bioRxiv · Dec 15, 2025 · PreprintBiochemistry