Sharon J. Sha

SPHERE enables the use of sensitive datasets in AI and open science by creating synthetic twins that preserve statistical properties and privacy.

This study identifies structural and molecular pathways affecting sustained attention in older adults, showing independent contributions of white matter integrity and preclinical Alzheimer's disease markers.

This study examines how APOE ε4 and Alzheimer's pathology interact to affect neural correlates of episodic memory in cognitively unimpaired older adults.

The paper examines how top-down attention and Alzheimer's pathology affect neural selectivity during learning in older adults, linking these factors to memory performance.

This study uses fMRI data from older adults to show that hippocampal activity and cortical reinstatement predict episodic memory performance, with age reducing cortical reinstatement and its link to memory.