Edward N. Wilson

This study identifies sex-specific changes in bone and senescence-related proteins in neurodegenerative diseases using plasma proteomics.

The paper introduces GlycoShuttles, mucin-binding protein shuttles that deliver therapeutics across the blood-brain barrier into brain cells, showing efficacy in dementia models.

This study examines how APOE ε4 and Alzheimer's pathology interact to affect neural correlates of episodic memory in cognitively unimpaired older adults.

CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).

The paper examines how top-down attention and Alzheimer's pathology affect neural selectivity during learning in older adults, linking these factors to memory performance.

This study shows that inhibiting IDO1 restores hippocampal glucose metabolism and rescues cognition in Alzheimer's disease models.

This study shows that TREM1 deficiency prevents age-related myeloid metabolic changes and cognitive decline in Alzheimer's disease models.

The paper examines the correlation between CSF sTREM2 and CSF tau levels in Parkinson’s disease and finds that sTREM2 is elevated in PD subgroups with abnormal tau but not Aβ.