Alexandra N. Trelle

This study identifies structural and molecular pathways affecting sustained attention in older adults, showing independent contributions of white matter integrity and preclinical Alzheimer's disease markers.

This study examines how APOE ε4 and Alzheimer's pathology interact to affect neural correlates of episodic memory in cognitively unimpaired older adults.

CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).

The paper examines how top-down attention and Alzheimer's pathology affect neural selectivity during learning in older adults, linking these factors to memory performance.

The paper assesses mnemonic and perceptual discrimination in older adults at risk for mild cognitive impairment, finding reduced entorhinal thickness and impaired discrimination in at-risk individuals.

This study uses fMRI data from older adults to show that hippocampal activity and cortical reinstatement predict episodic memory performance, with age reducing cortical reinstatement and its link to memory.

The paper investigates age-related changes in representational quality and retrieval processes using neural differentiation and BOLD activity analysis during memory tasks.