Author

Jack A. Roth

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3670-5745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Elizabeth J. ShpalliD· 1 shared Feng Meng· 1 shared Ismail Mustafa MeraziD· 1 shared Jing WangiD· 1 shared Lihui Gao· 1 shared Mourad Majidi· 1 shared Qi WangiD· 1 shared Renduo Song· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Elizabeth J. ShpallORCID

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1 paper

Recent·Most cited

NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model

Ismail Mustafa Meraz, Mourad Majidi, Renduo Song, Feng Meng, Lihui Gao, Qi Wang, Jing Wang, Elizabeth J. Shpall, Jack A. Roth

This study shows NPRL2 gene therapy reduces lung metastases in KRAS/STK11 mutant NSCLC in humanized mice by enhancing immune cell infiltration and reducing T cell inhibitory signals.

eLife · Jul 9, 2024Peer-reviewedCancer Biology