Mark Andrew Espeland

The paper examines if a genetic risk score for cup-to-disc ratio modifies the link between large CDR and cognitive function in women, finding that large CDR is still associated with lower cognitive scores even after accounting for genetic risk.

The paper identifies 617 novel genomic loci and pathways associated with structural covariance patterns in the human brain using a stochastic multivariate factorization method.

The paper identifies pseudoreplication bias in single-cell studies and proposes mixed models to address it, improving statistical inference and study design.