G. Sampath

The paper proposes a minimalist binary/digital method for single molecule protein identification using optically labeled tRNAs and carboxypeptidases, achieving high identification rates for human peptides.

The paper models a computational method to sequence and quantify whole proteins without proteolysis, using nanopore translocation and signal analysis.

The paper demonstrates a minimalist method for protein identification using isoelectric point and nanopore measurements, achieving over 90% identification rates across multiple proteomes.