Author

J. C. Lagarde

University of California, Los AngelesORCID 0000-0002-3738-3119Unclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron S. MeyeriD· 1 shared Farnaz MohammadiiD· 1 shared Laura M. HeiseriD· 1 shared Luka KarginoviD· 1 shared Sean M. GrossiD· 1 shared Shakthi VisaganiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperSystems Biology

Aaron S. MeyerORCID

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1 paper

Recent·Most cited

Systems BiologybioRxivPreprintJun 25, 2021

A lineage tree-based hidden Markov model to quantify cellular heterogeneity and plasticity

Farnaz Mohammadi, Shakthi Visagan, Sean M. Gross…·Aaron S. Meyer

This paper introduces a lineage tree-based hidden Markov model to quantify cellular heterogeneity and plasticity using single-cell lineage data, showing it can classify distinct phenotypic states and drug responses in cancer and non-cancer cell populations.

1 citation

humanmouse

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