Generation of a zebrafish neurofibromatosis model via inducible knockout of nf2
Desingu Ayyappa Raja, Yuanyun Huang, Jan Štundl, Katelyn Chu, Anushka Irodi, Zihan Yang, Brian E. Applegate, Marianne E. Bronner-Fraser
This study generates a zebrafish model of neurofibromatosis by inducible knockout of nf2a/b, revealing tumor development similar to human NF-2.
bioRxiv · Apr 23, 2024 · PreprintDevelopmental Biology