GenomicsbioRxivPreprint
Dissecting sequence determinants of DNA methylation and in silico perturbation
Fa‐Ming Chen, Qinhao Zhang, Shiwei Zhu…·Fulong Yu
This paper introduces MethylAI, a deep learning framework that predicts DNA methylation states from genomic sequence and identifies sequence determinants of methylation through in silico perturbation.
DOI 10.1101/2025.11.20.689274