Hannah E. Bowrey

Chemogenetic stimulation of a retinal circuit activates brain noradrenergic neurons, prevents apoptosis, and suppresses depression-like behaviors

The paper demonstrates that chemogenetic activation of a retinal circuit prevents depression-like behaviors and LC noradrenergic system pathology caused by light deprivation.

Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats

This study shows that demand elasticity in rats predicts addiction endophenotypes and the effectiveness of an orexin-1 receptor antagonist in reducing cocaine-seeking behavior.

Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats

This study shows that intermittent cocaine access increases orexin neuron activity in the lateral hypothalamus, contributing to addiction-like behaviors in rats.