Author

Junyan Xu

National Institutes of HealthORCID 0000-0002-3789-2319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Assay:metagenomics· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

S. Cenk ŞahinalpiD· 3 shared Kaiyuan ZhuiD· 2 shared Adelani Adeleye· 1 shared Alejandro A. SchäfferiD· 1 shared Ananth HariiD· 1 shared Andrea BiondiiD· 1 shared Andrew J. OleriD· 1 shared Camille AlbaiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioinformatics

S. Cenk ŞahinalpORCID

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Author profile →

3 papers

Recent·Most cited

Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS

Junyan Xu, Kaiyuan Zhu, Jieling Cai, Can Koçkan, Natnatee Dokmai, Hyunghoon Cho, David Paul Woodruff, S. Cenk Şahinalp

The paper improves the SkSES method for privacy-preserving GWAS by integrating a learning-augmented approach, achieving up to 40% higher accuracy under memory constraints.

iScience · Feb 13, 2025Peer-reviewedBioinformatics

Strain Level Microbial Detection and Quantification with Applications to Single Cell Metagenomics

Kaiyuan Zhu, Alejandro A. Schäffer, Welles Robinson, Junyan Xu, Eytan Ruppin, Funda Ergün, Yuzhen Ye, S. Cenk Şahinalp

CAMMiQ improves microbial strain-level detection and quantification in single-cell metagenomics by using combinatorial optimization and doubly-unique substrings, outperforming existing methods in accuracy.

Nature Communications · Oct 28, 2022Peer-reviewedBioinformatics

ImmunoTyper-SR: A Novel Computational Approach for Genotyping Immunoglobulin Heavy Chain Variable Genes using Short Read Data

Michael K.B. Ford, Ananth Hari, Oscar L. Rodriguez, Junyan Xu, Justin Lack, Cihan Oguz, Yu Zhang, Andrew J. Oler, Ottavia M. Delmonte, Sarah E. Weber, Mary Magliocco, Jason Barnett, Sandhya Xirasagar, Smilee Samuel, Luisa Imberti, , S. Cenk Şahinalp

ImmunoTyper-SR genotypes IGHV alleles from short read data and identifies associations between IGHV alleles and anti-type I IFN autoantibodies in COVID-19 patients.

Cell Systems · Oct 1, 2022Peer-reviewedBioinformatics