Author

Aaron J. Sams

ORCID 0000-0002-3800-4459Unclaimed ORCID profile · follow to get notified of new preprints

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Aaron J. Sams1 paper

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam R. BoykoiD· 3 shared Erin T. ChuiD· 2 shared Andrea SlavneyiD· 1 shared Kelly J. Diehl· 1 shared Missy J. SimpsoniD· 1 shared Petra E. Deane‐Coe· 1 shared Rodney L. PageiD· 1 shared

Activity by Year

2018-2019 · peak 2/yr

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7 top collaborators · 15 mutual co-author links

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3 shared papersGenomics

Adam R. BoykoORCID

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3 papers

Recent·Most cited

GenomicsMammalian GenomePeer-reviewedMay 21, 2019

Inbreeding depression causes reduced fecundity in Golden Retrievers

Erin T. Chu, Missy J. Simpson, Kelly J. Diehl…·Adam R. Boyko

The paper examines the relationship between inbreeding depression and fecundity in Golden Retrievers using genomic data from the Golden Retriever Lifetime Study.

29 citations

statistical model

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BioinformaticsPLoS GeneticsPeer-reviewedOct 4, 2018

Direct-To-Consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication causing blue eyes and heterochromia in Siberian Huskies

Petra E. Deane‐Coe, Erin T. Chu, Andrea Slavney…·Aaron J. Sams

A consumer genomics study of 6,000 dogs identifies a 98.6-kb duplication linked to blue eyes and heterochromia in Siberian Huskies through a large-scale GWAS.

34 citations

whole-genome sequencingstatistical model

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GenomicsbioRxivPreprintMay 7, 2018

Fine-scale resolution and analysis of runs of homozygosity in domestic dogs

Aaron J. Sams, Adam R. Boyko

The paper analyzes runs of homozygosity (ROH) in domestic dogs to assess their contribution to inbreeding depression, finding that both long and short ROH contribute to autozygosity at deleterious loci.

1 citation

mousewhole-genome sequencing

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