Adam R. Boyko

This paper introduces Mikado, a method using sparse linear algebra to accelerate genotype representation graph computations, significantly improving speed over existing tools on large biobank datasets.

This study uses a genotype-first approach to identify new mutations related to craniofacial morphology and stature in dogs, highlighting the role of allelic heterogeneity in breed trait selection.

This study uses a dense genotyping array to identify genome-wide associations for three complex feline diseases in a multi-breed cohort of cats.

The paper assembles a Great Dane genome using long-read sequencing, revealing improvements over the Boxer-derived reference and highlighting retrotransposon activity in canine genetic variation.

The paper identifies FBXW7 mutations as a prognostic marker in canine B-cell lymphoma using exome sequencing and clinical data.

The paper improves genome-wide association studies in dogs by imputing variants from 365 whole-genome sequences, increasing marker count 130-fold and enhancing power for complex trait mapping.

The paper examines the relationship between inbreeding depression and fecundity in Golden Retrievers using genomic data from the Golden Retriever Lifetime Study.

A consumer genomics study of 6,000 dogs identifies a 98.6-kb duplication linked to blue eyes and heterochromia in Siberian Huskies through a large-scale GWAS.

The paper analyzes runs of homozygosity (ROH) in domestic dogs to assess their contribution to inbreeding depression, finding that both long and short ROH contribute to autozygosity at deleterious loci.