Author

Frank Pui-Ling Lai

Queen Mary HospitalORCID 0000-0002-3801-8498Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Annie S.Y. ChaniD· 1 shared April ChaniD· 1 shared Clara Sze-Man TangiD· 1 shared Dessy ChaniD· 1 shared Esw NganiD· 1 shared Hans C. CleversiD· 1 shared Helen H N YaniD· 1 shared Ho Sang HuiiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Annie S.Y. ChanORCID

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2 papers

Recent·Most cited

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression

Sarah S K Yue, Yin Tong, Hoi Cheong Siu, Siu Lun Ho, Simon Ying-Kit Law, Wai Yin Tsui, Dessy Chan, Yuanhua Huang, Annie S.Y. Chan, Shui Wa Yun, Ho Sang Hui, Jee-Eun Choi, Matthew HSU, Frank Pui-Ling Lai, April Chan, , Helen H N Yan

Gut · Nov 20, 2024Peer-reviewedCancer Biology

Whole-genome analysis of noncoding genetic variations identifies multigranular regulatory element perturbations associated with Hirschsprung disease

Xi Fu, Kathy Nga-Chu Lui, Clara Sze-Man Tang, Ray Kit Ng, Frank Pui-Ling Lai, Sin-Ting Lau, Zhixin Li, María-Mercé García-Barceló, Pak Chung Sham, Paul Kwong Hang Tam, Esw Ngan, Kevin Yuk-Lap Yip

The paper identifies noncoding genetic variants associated with Hirschsprung disease using a framework that captures multi-granular regulatory element perturbations.

Genome Research · Nov 1, 2020Peer-reviewedGenetics