Author

Simon Ying-Kit Law

Queen Mary HospitalORCID 0000-0002-6518-5806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Helen H. N. YaniD· 2 shared Siu Tsan YueniD· 2 shared Suet Yi LeungiD· 2 shared Alfred King-yin LamiD· 1 shared Annie S.Y. ChaniD· 1 shared Anthony W.I. LoiD· 1 shared April ChaniD· 1 shared B. T.-t. Law· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenomics

Helen H. N. YanORCID

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3 papers

Recent·Most cited

GenomicsNaturePeer-reviewedMar 19, 2025

The somatic mutation landscape of normal gastric epithelium

Tim H. H. Coorens, Grace Collord, Hyungchul Jung…·Michael R. Stratton

This study uses whole-genome sequencing to analyze somatic mutations in normal gastric epithelium, revealing mutation rates, clonal dynamics, and associations with cancer risk factors.

57 citationstop 1%

humanwhole-genome sequencing

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Cancer BiologyGutPeer-reviewedNov 20, 2024

Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression

Sarah S K Yue, Yin Tong, Hoi Cheong Siu…·Helen H N Yan

44 citationstop 2%

humanscRNA-seq

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Cancer BiologyCancer LettersPeer-reviewedMay 31, 2024

ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma

Valen Zhuoyou Yu, Shan Shan So, Bryan Chee-chad Lung…·Maria Li Lung

This study identifies ΔNp63's role in restricting viral mimicry response in ESCC, reducing cell viability, and modulating tumor microenvironment immune cells.

14 citations

humanbulk RNA-seq

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