Collapse of Interictal Suppressive Networks Permits Seizure Spread
Ghassan S. Makhoul, Derek J. Doss, Graham Walter Johnson…·Dario J. Englot
This paper analyzes peri-ictal network dynamics in drug-resistant epilepsy patients to show that NIZs increase inhibitory signaling to SOZs during seizures, but this suppression is insufficient to prevent seizure onset.