Natan Belchikov

The paper introduces a spatial long-read sequencing method to study developmental splicing and polyadenylation changes in cortical layers and cell types, finding layer-specific and age-related regulatory patterns.

The paper predicts cell-type-specific exon inclusion in human brain cells using RBP binding sites and genomic sequence, revealing more complex splicing mechanisms in neurons than glia.

The paper introduces ScISOr-ATAC to measure splicing and chromatin accessibility in frozen brain tissues, finding convergent and divergent patterns in different cell types and conditions.

Ariadne deconvolves synthetic long read data using assembly graphs to improve taxonomic classification and de novo assembly of complex populations.

This study compares 10x Genomics 3' and 5' assays using short and long reads, finding differences in exonic/intronic capture and transcript completeness.

The paper introduces SnISOr-Seq, a method for single-nuclei isoform RNA sequencing, and finds distinct combination patterns of transcript elements in human brain cell types.