Mapping and reprogramming human tissue microenvironments with MintFlow
Amir Akbarnejad, Lloyd Steele, Daniyal J. Jafree, Sebastian Birk, Marta Rosa Sallese, Koen Rademaker, Adam R. Boxall, Benjamin M. Rumney, Catherine L. Tudor, Minal J Patel, Martin Prete, Stanislaw Makarchuk, Colin Y.C. Lee, Jonas Maaskola, Tong Li, , Mohammad Lotfollahi
MintFlow is a generative AI algorithm that predicts how tissue perturbations reprogram cell states in disease, revealing novel cell populations and therapeutic targets in three human conditions.
bioRxiv · Jun 24, 2025 · PreprintGenomics