Multi-Enzyme Data-Independent Acquisition Mass Spectrometry for Proteoform-Aware Single-shot Proteomics
Moritz Heusel, Lotta Happonen, Christofer A.Q. Karlsson, Emma Ahrman, Johan Malmstrom
The paper introduces mE-DIA, a multi-enzyme DIA-MS workflow that improves proteoform detection in proteomics by integrating analysis and interpretation into a single toolset.
bioRxiv · Nov 9, 2026 · PreprintSystems Biology