ImmunologybioRxivPreprint
Identification and characterization of neoantigen-reactive CD8+ T cells following checkpoint blockade therapy in a pan-cancer setting
Keith Henry Moss, Ulla Kring Hansen, Vinicius Araújo Barbosa de Lima…·Sine Reker Hadrup
The paper detects neoantigen-reactive CD8+ T cells in tumor biopsies and peripheral blood post-checkpoint blockade therapy and identifies peptide hydrophobicity and treatment-induced phenotypes as factors influencing their response.
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