Author

Yasuhiro Takenaka

Nippon Medical SchoolORCID 0000-0002-3874-1803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ikuo InoueiD· 2 shared Masataka HirasakiiD· 2 shared Yoshihiko KakinumaiD· 2 shared Akihiko OkudaiD· 1 shared Akira ShimadaiD· 1 shared Hajime Kamezawa· 1 shared Hidekazu Aochi· 1 shared Hidemasa U. BonoiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersBiochemistry

Ikuo InoueORCID

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 10, 2026

Predicted structure of the 89-kDa invasion-tip protein of Holospora obtusa, an endonuclear symbiont of Paramecium caudatum, suggests a pH-dependent conformational change

Yasuhiro Takenaka, Toshiyuki Murai, Toru Nakatsu…·Masahiro Fujishima

The paper predicts the structure of a 89-kDa invasion-tip protein from Holospora obtusa and suggests a pH-dependent conformational change may aid in escaping the host digestive vacuole.

DOI 10.64898/2026.10.08.757700

protein structuredeep learning

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BiochemistrybioRxivPreprintApr 26, 2025

Fluorescence analysis of serum lipoproteins using a histidine-imidazole polyacrylamide slab gel electrophoresis method

Yasuhiro Takenaka, Ikuo Inoue, Masaaki Ikeda, Yoshihiko Kakinuma

The paper introduces a high-throughput, cost-effective fluorescence-based PAGE method for analyzing lipoproteins in human serum, showing improved sensitivity and quantitative accuracy.

DOI 10.1101/2025.04.26.650752

humanproteomics

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Molecular BiologyJournal of Cardiovascular PharmacologyPeer-reviewedFeb 29, 2024

Transcriptome Analysis Reveals Enhancement of Cardiogenesis-Related Signaling Pathways by S-nitroso-N-pivaloyl-D-penicillamine (SNPiP): Implications for Improved Diastolic Function and Cardiac Performance

Yasuhiro Takenaka, Masataka Hirasaki, Hidemasa U. Bono…·Yoshihiko Kakinuma

This study uses transcriptome analysis to show SNPiP enhances cardiogenesis-related pathways and improves cardiac function in mice.

6 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintMay 28, 2020

Targeted disruption of Pparγ1 promotes trophoblast endoreplication in the murine placenta

Takanari Nakano, Hidekazu Aochi, Masataka Hirasaki…·Ikuo Inoue

This study shows that Pparγ1 disruption in mice leads to trophoblast endoreplication defects in the placenta, affecting placental growth and survival.

1 citation

mousebulk RNA-seq

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