GeneticsThe American Journal of Human GeneticsPeer-reviewed
Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation
Victoria L. Wyckelsma, Tomas Venckūnas, Peter J. Houweling…·Håkan Westerblad
The paper shows that absence of α-actinin-3 in humans improves cold resilience through changes in skeletal muscle thermogenesis and myosin heavy chain composition.
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