Author

Aleksandra Otwinowska

University of WrocławORCID 0000-0002-3911-5409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Assay:protein sequence· 1

Frequent Co-Authors

Sebastian OlejniczakiD· 3 shared Zuzanna Drulis‐KawaiD· 3 shared Barbara MaciejewskaiD· 2 shared Janusz KoszuckiiD· 2 shared Maria PozniakiD· 2 shared Rafal J. MostowyiD· 2 shared Vyshakh R. Panicker· 2 shared Agnieszka ŁątkaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMicrobiology

Sebastian OlejniczakORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

DepoCat: Interactive database of experimentally verified phage depolymerases

Sebastian Olejniczak, Aleksandra Otwinowska, Maria Pozniak, Zuzanna Drulis‐Kawa

DepoCat is a database of experimentally verified phage depolymerases that enables sequence and structure-based classification and specificity prediction.

bioRxiv · Sep 17, 2026 · PreprintMicrobiology

Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes

Aleksandra Otwinowska, Janusz Koszucki, Vyshakh R. Panicker, Jade Leconte, Sebastian Olejniczak, Kathryn E. Holt, Edward J. Feil, Eduardo P. C. Rocha, Bogna J. Smug, Barbara Maciejewska, Zuzanna Drulis‐Kawa, Rafal J. Mostowy

This study identifies prophage-encoded receptor-binding proteins (RBPs) mediating capsule specificity in Klebsiella pneumoniae, revealing structural diversity and functional activity beyond classical depolymerases.

PLoS Biology · Apr 28, 2026Peer-reviewedMicrobiology

DepoCatalog: Mapping the Diversity of 105 Recombinant Klebsiella Phage Depolymerases Across Sequence, Structure, and Substrate Specificity

Aleksandra Otwinowska, Sebastian Olejniczak, Agnieszka Łątka, Maria Pozniak, Grażyna Majkowska-Skrobek, Barbara Maciejewska, Janusz Koszucki, Vyshakh R. Panicker, Sara Jabłońska, Mathilde Hulsens, Joachim J. Bugert, Régis Tournebize, Stan J. J. Brouns, Flavia Squeglia, Rita Berisio, , Zuzanna Drulis‐Kawa

The paper catalogs 105 recombinant Klebsiella phage depolymerases, classifying them by sequence, structure, and substrate specificity, revealing diverse enzyme functions and evolutionary patterns.

bioRxiv · Sep 9, 2025 · PreprintMicrobiology