Universe of Lasso Proteins: Exploring the limit of entanglement and folding landscape of proteins predicted by AlphaFold
Fernando Bruno da Silva, Agata P. Perlinska, Jacek Płonka, Erica Flapan, Joanna Ida Sulkowska
The paper uses AlphaFold to analyze protein structures and identifies new lasso motifs, including knotted lasso proteins, and explores their topological complexity and conservation.
bioRxiv · Mar 21, 2025 · PreprintBiophysics