GLUT5 armouring enhances adoptive T cell therapy anti-tumour activity under glucose-limiting conditions
Robert Lee Page II, Olivier Martínez, Daniel Larcombe-Young, Eva Bugallo-Blanco, Sophie Papa, Esperanza Perucha
This paper shows that modifying T cells to use fructose via GLUT5 improves their anti-tumor activity in low-glucose environments.
Immunotherapy Advances · Dec 30, 2024Peer-reviewedCancer Biology