Coated Bacterial Vaccine Platform Overcomes Weak Antigen Immunogenicity: A Functional Approach to GnRH-Based Immunocastration
Inés Harguindeguy, Matías H. Assandri, María Antonieta Daza Millone, Sebastián Cavalitto, María de los Ángeles Serradell, Gastón E. Ortiz
This study demonstrates that Coated Bacterial Vaccines (CBVs) enhance the immunogenicity of a GnRH-based peptide vaccine, inducing a strong Th2-biased humoral response and effective immunocastration in mice.
Biotechnology Journal · Jun 1, 2026Peer-reviewedImmunology