An archaic reference-free method to jointly infer Neanderthal and Denisovan introgressed segments in modern human genomes
Léo Planche, Anna Vasil'evna Il'ina, María C. Ávila‐Arcos, Flora Jay, Emilia Huerta‐Sánchez, Vladimir Shchur
DAIseg is a new HMM-based method that detects both Neanderthal and Denisovan introgression in modern human genomes without archaic references, outperforming existing methods in Papuan populations.
Molecular Biology and Evolution · Sep 15, 2026Peer-reviewedBioinformatics