Emilia Huerta‐Sánchez

DAIseg is a new HMM-based method that detects both Neanderthal and Denisovan introgression in modern human genomes without archaic references, outperforming existing methods in Papuan populations.

TRACTINATOR infers continental and archaic ancestry in admixed genomes using deep learning, revealing archaic introgression patterns in Latin American populations.

This paper investigates using imputation to improve archaic ancestry inference in ancient human genomes, showing that imputed genomes can reliably detect and quantify introgression and identify introgressed segments.

The paper examines the effects of Neanderthal introgressed alleles on brain morphology and neuropsychiatric traits using UK Biobank data, identifying associations with specific brain regions and mental health outcomes.

This paper evaluates neural network-based methods for local ancestry inference in challenging admixture scenarios and finds they perform best with specialized preprocessing.

This study identifies ancient S. enterica Paratyphi C DNA in 19th-century Mexico, linking it to European strains and showing its persistence in urban settings.

This study shows natural selection reduces the accuracy of polygenic scores in predicting traits from ancient humans by altering genetic variation patterns.

This study introduces a frugal diffusion model for generating artificial genomes and evaluates its utility for local ancestry inference using synthetic and real data.

This study benchmarks haplotype inference methods on ancient DNA by simulating aDNA data and shows that accurate phasing is possible even for very ancient individuals with sufficient contamination control and read depth.

The paper analyzes pre-Hispanic genetic data from Mexico to show population continuity despite climate change and identifies an ancient unsampled ghost population's contribution.

This study examines how recent admixture in the Americas affects the distribution of archaic ancestry, finding a positive correlation between non-African ancestry and archaic alleles.

The paper investigates whether forensic STRs correlate with gene expression levels, finding six significant associations that may compromise medical privacy.

This study examines the distribution of archaic genetic variation in Eurasian populations, finding distinct patterns of archaic ancestry and suggesting complex interactions between modern humans and archaic populations.

The paper analyzes ABO genetic variation in Neanderthals and Denisovans, finding Neanderthal-derived alleles in modern humans and suggesting balancing selection.