Computer-guided Binding Mode Identification and Affinity Improvement of an LRR Protein Binder without Structure Determination
Yoonjoo Choi, Sukyo Jeong, Jung-Min Choi, Christian Ndong, Karl E. Griswold, Chris Bailey‐Kellogg, Hak‐Sung Kim
The paper develops a method combining computational and experimental approaches to identify binding modes and improve affinity of an LRR protein binder without structure determination.
PLoS Computational Biology · Aug 31, 2020Peer-reviewedBioinformatics