ASIGNTF: AGNOSTIC SIGNATURE USING NTF: A UNIVERSAL AGNOSTIC STRATEGY TO ESTIMATE CELL-TYPES ABUNDANCE FROM TRANSCRIPTOMIC DATASETS
Paul Fogel, Galina Boldina, Corinne Rocher, Charles Bettembourg, George Luta, Franck Augé
The paper introduces ASigNTF, a method to estimate cell-type abundance from transcriptomic data using non-negative tensor factorization and the Herfindahl-Hirschman index, and provides two new immune cell-type signatures that outperform existing methods.
bioRxiv · Feb 4, 2021 · PreprintBioinformatics