A CellAge epigenetic clock for expedited discovery of anti-ageing compounds
Celia Lujan, Eleanor J. Tyler, Simone Ecker, Amy P. Webster, Eleanor Rachel Stead, Victoria Eugenia Martinez-Miguel, Deborah Milligan, James C. Garbe, Martha R. Stampfer, Stephan Beck, Robert Lowe, Cleo L. Bishop, Ivana Bjedov
The paper develops CellAgeClock, an epigenetic clock to measure ageing in human cells, identifies anti-ageing drugs, and validates their efficacy in vivo.
bioRxiv · May 22, 2020 · PreprintMolecular Biology